Backdrop to the development of Brazil's national COVID-19 immunization plan. / Contexto de elaboração do Plano de Imunização contra COVID-19 no Brasil.

The process of developing Brazil's COVID-19 immunization plan began belatedly and involved a number of experts, including a technical group responsible for defining priority groups for vaccination. This process was permeated by contradictions between the government and researchers. Finally, on 20 January 2021, the government published an updated version of the plan, which remains limited in scope.

O processo de elaboração do Plano de Imunização contra Covid-19 no Brasil se iniciou tardiamente e contou com a participação de especialistas incluindo o grupo técnico responsável pela definição de grupos prioritários para a vacinação. Este processo foi permeado de indefinições entre o Governo Federal e pesquisadores e, finalmente, no dia 20 de janeiro de 2021 foi divulgada a versão atualizada do Plano ainda incipiente no que tange a sua abrangência.

People with Disabilities and COVID-19 in the state of Espírito Santo, Brazil: between invisibility and lack of Public Policies. / Pessoas com Deficiência e COVID-19 no estado do Espírito Santo, Brasil: entre a invisibilidade e a falta de Políticas Públicas.

This article aims to analyze the profile of people with disabilities among the cases notified by the COVID-19 panel of Espírito Santo and the possible associations with the positive result of the COVID-19 test. Descriptive cross-sectional study among people with disabilities with positive and negative tests for the diagnosis of COVID-19. Associations of epidemiological and clinical variables were performed using the chi-square test and logistic regression models to estimate the odds ratio. Lethality rate of COVID-19 was 4.9% (175 cases) in the group of people with disabilities, and 3% (3,016) in the group without disabilities. People with disabilities, male (OR=1.34; 95%CI 1.22-1.47), race/black color (OR=1.55; 95%CI 1.09-2.20), and those who were hospitalized (OR=2.27; 95%CI 1.71-3.02) were associated with positive tests for COVID-19. The pandemic emphasizes the need to create specific legal care mechanisms and targeted public policies for this population.

O objetivo deste artigo é analisar o perfil das pessoas com deficiência dentre os casos notificados pelo painel COVID-19 do Espírito Santo e possíveis associações com o resultado positivo do teste COVID-19. Estudo Transversal descritivo entre as pessoas com deficiência com testes positivos e negativos para o diagnóstico de COVID-19. Foram realizadas associações das variáveis epidemiológicas e clínicas, utilizando o teste qui-quadrado e modelos de regressão logística para se estimar o odds ratio. A letalidade por COVID-19 foi de 4,9% (175 casos) no grupo das pessoas com deficiência, e 3% (3.016) no grupo sem deficiência. Pessoas com deficiência do sexo masculino (OR=1,34; IC95% 1,22-1,47), raça/cor preta (OR=1,55; IC95% 1,09-2,20), e as que ficaram internadas (OR=2,27; IC95% 1,71-3,02) apresentaram associação com testes positivos para COVID-19. A pandemia enfatiza a necessidade de criar mecanismos legais de cuidados específicos e políticas públicas focalizadas para essa população.

[Barriers and facilitators to confronting HIV/aids and syphilis experienced by Venezuelan women living in BrazilFactores facilitadores y barreras que tienen las mujeres venezolanas residentes en Brasil respecto de la infección por el VIH/sida y la sífilis]. / Barreiras e facilitadores do enfrentamento de HIV/aids e sífilis por venezuelanas residentes no Brasil.

Objective: To describe the perception of Venezuelan women regarding access to health care, diagnosis, and treatment of HIV/aids and syphilis in Brazil. Method: This is a descriptive, exploratory study employing a qualitative approach, performed from February to May 2021 in the municipalities of Manaus, state of Amazonas, and Boa Vista, state of Roraima. The interviews with participants were fully transcribed, with identification of themes based on content analysis. Results: Forty women were interviewed (20 in Manaus and 20 in Boa Vista). Following transcription and translation of the accounts, two analytical categories were identified: barriers to healthcare access, with four subcategories - language, cost, adverse drug reactions, and COVID-19 pandemic; and facilitators of healthcare access, again with four subcategories - Unified Health System (SUS), National Policy of Comprehensive Women's Health, National Social Assistance Policy, and relationship between healthcare professionals and SUS users. Conclusion: The results showed the need to design strategies to mitigate the difficulties faced by migrant women from Venezuela living in Brazil regarding the diagnosis and treatment of HIV/aids and syphilis, going beyond the healthcare support guaranteed by law.

Objetivo: Describir la percepción de las mujeres venezolanas sobre el acceso a los servicios de salud, al diagnóstico y al tratamiento de la infección por el VIH/sida y la sífilis en Brasil. Métodos: Se trata de un estudio descriptivo y exploratorio, con enfoque cualitativo, realizado entre febrero y mayo del 2021 en los municipios de Manaos, estado de Amazonas, y Boa Vista, estado de Roraima. Las entrevistas con las participantes se transcribieron en su totalidad, y se exploraron los puntos de interés según el análisis del contenido. Resultados: Se entrevistaron 40 mujeres (20 en Manaos y 20 en Boa Vista). A partir de la transcripción y la traducción de las conversaciones, se establecieron dos categorías para el análisis del contenido: las barreras de acceso a los servicios de salud (subcategorías: idioma, costos relacionados con la salud, reacciones adversas a los medicamentos y pandemia de COVID-19); y los factores facilitadores del acceso (cuatro subcategorías: Sistema Único de Salud, Política nacional de Atención Integral a la Salud de la Mujer, Política Nacional de Asistencia Social y relación entre los profesionales de salud y las usuarias del Sistema Único de Salud). Conclusión: Los resultados mostraron la necesidad de formular estrategias para mitigar las dificultades que enfrentan las mujeres migrantes de Venezuela residentes en Brasil en relación con el diagnóstico y el tratamiento de la infección por el VIH/sida y la sífilis, más allá de la protección de la salud garantizada por la ley.

Barreiras e facilitadores do enfrentamento de HIV/aids e sífilis por venezuelanas residentes no Brasil Barriers and facilitators to confronting HIV/aids and syphilis experienced by Venezuelan women living in Brazil Factores facilitadores y barreras que tienen las mujeres venezolanas residentes en Brasil respecto de la infección por el VIH/sida y la sífilis

RESUMO Objetivo. Descrever a percepção de mulheres venezuelanas sobre o acesso aos serviços de saúde, ao diagnóstico e ao tratamento de HIV/aids e sífilis no Brasil. Métodos. Trata-se de um estudo descritivo e exploratório, com abordagem qualitativa, realizado no período de fevereiro a maio de 2021 nos municípios de Manaus, estado do Amazonas, e Boa Vista, estado de Roraima. As entrevistas com as participantes foram transcritas na íntegra, com levantamento de temas a partir de análise de conteúdo. Resultados. Foram entrevistadas 40 mulheres (20 em Manaus e 20 em Boa Vista). A partir da transcrição e tradução das falas, foram identificadas duas categorias de análise de conteúdo: barreiras de acesso aos serviços de saúde, com quatro subcategorias — idioma, custos com saúde, reações adversas ao medicamento e pandemia de covid-19;e facilitadores do acesso, com quatro subcategorias — Sistema Único de Saúde, Política Nacional de Atenção Integral à Saúde da Mulher, Política Nacional de Assistência Social e relação entre profissional de saúde e usuária do Sistema Único de Saúde. Conclusão. Os resultados mostraram a necessidade de elaborar estratégias para mitigar as dificuldades enfrentadas pelas mulheres migrantes da Venezuela residentes no Brasil quanto ao diagnóstico e tratamento de HIV/aids e sífilis, indo além do amparo à saúde garantido pela lei.

Prevalence of tuberculosis, COVID-19, chronic conditions and vulnerabilities among migrants and refugees: An electronic survey

Objective: to analyze the prevalence of tuberculosis, coronavirus, chronic conditions and vulnerabilities among migrants and refugees in Brazil. Method: this is a cross-sectional study of the electronic survey type conducted with international migrants during the COVID-19 pandemic. Descriptive statistics was applied for the analysis, with calculation of position and dispersion measures. Regarding the categorical variables, relative and absolute frequencies were estimated. Results: the study participants were 553 migrants and refugees, verifying 3.07%, 7.2% and 27.3% prevalence of tuberculosis, COVID-19 and chronic conditions, respectively. Among the vulnerabilities, 32% reported unemployment, 37.6% moved to Brazil as a result of the social situation in their countries and 33.6% were living as refugees or sheltered people. Conclusion: tuberculosis, chronic diseases and COVID-19 presented higher prevalence values in migrants and refugees than in the general population. As this is a population group that still has significant difficulty accessing health services and social protection systems, based on diverse evidence, the study will subsidize public policies, Nursing care and the incorporation of new routines in the service. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

Prevalence of tuberculosis, COVID-19, chronic conditions and vulnerabilities among migrants and refugees: an electronic survey.

OBJECTIVE: to analyze the prevalence of tuberculosis, coronavirus, chronic conditions and vulnerabilities among migrants and refugees in Brazil. METHOD: this is a cross-sectional study of the electronic survey type conducted with international migrants during the COVID-19 pandemic. Descriptive statistics was applied for the analysis, with calculation of position and dispersion measures. Regarding the categorical variables, relative and absolute frequencies were estimated. RESULTS: the study participants were 553 migrants and refugees, verifying 3.07%, 7.2% and 27.3% prevalence of tuberculosis, COVID-19 and chronic conditions, respectively. Among the vulnerabilities, 32% reported unemployment, 37.6% moved to Brazil as a result of the social situation in their countries and 33.6% were living as refugees or sheltered people. CONCLUSION: tuberculosis, chronic diseases and COVID-19 presented higher prevalence values in migrants and refugees than in the general population. As this is a population group that still has significant difficulty accessing health services and social protection systems, based on diverse evidence, the study will subsidize public policies, Nursing care and the incorporation of new routines in the service.

SARS-CoV-2 infection prevalence and associated factors: a serial population-based study in Espírito Santo, Brazil, May to June 2020. / Prevalência e fatores associados à infecção por SARS-CoV-2: estudo de base populacional seriado, no Espírito Santo, de maio a junho/2020.

OBJECTIVE: To analyze SARS-CoV-2 seroprevalence and association of sociodemographic and clinical aspects in the state of Espírito Santo, Brazil. METHODS: This was a serial cross-sectional study carried out in four phases, using households as the unit of analysis, from May to June 2020. Eleven municipalities were surveyed, with a sample of 4,500 households in each phase. RESULTS: Prevalence ranged from 2.1% (95%CI 1.7;2.5) on May 10 (first phase) to 9.6% (95%CI 8.8;10.4) on June 21 (fourth phase). In the Greater Vitória Metropolitan Region, the prevalence were 2.7% (95%CI 2.2;3.3) in the first phase, and 11.5% (95%CI 10.5;12.6) in the fourth phase; in the interior region of the state, prevalence ranged from 0.4% (95%CI 0.1;0.9) to 4.4% (95%CI 3.2;5.5) between the two phases. CONCLUSION: The increase in SARS-CoV-2 seroprevalence found in the fourth phase highlighted the high transmission of the virus, information that can support management of the pandemic.

Serological prevalence of SARS-CoV-2 infection among prison system workers in the state of Espírito Santo, Brazil, 2020. / Prevalência sorológica de infecção por SARS-CoV-2 entre trabalhadores do sistema prisional do Espírito Santo, 2020.

OBJECTIVE: To estimate the serological prevalence of SARS-CoV-2 infection among prison system workers in the state of Espírito Santo, Brazil, between August-September 2020. METHODS: This was a stratified sample survey, using interviews and serological tests for SARS-CoV-2. RESULTS: Among the 986 interviewers, the serological prevalence of SARS-CoV-2 infection was 11.9% (95%CI 8.1%;15.7%) in health professionals, and 22.1% (95%CI 18.8%;25.3%) in prison officers. Positivity was more frequent among health professionals in the north of the state (19.7%) and in male prison officers (24.0%). Among seropositive individuals, fatigue was the most frequent symptom in prison agents (13.4%) and myalgia in health professionals (10.8%); and the most prevalent comorbidities among the seropositive individuals were asthma or bronchitis (16.2%), in health professionals, and hypertension in prison officers (12.8%). CONCLUSION: The serological prevalence of SARS-Cov-2 infection was higher in prison officers, a finding that can support disease control and prevention actions in this scenario.

COVID-19 in children, adolescents and young adults: a cross-sectional study in Espírito Santo, Brazil, 2020. / COVID-19 em crianças, adolescentes e jovens: estudo transversal no Espírito Santo, 2020.

OBJECTIVE: To analyze self-reported sociodemographic and clinical characteristics among individuals aged 2 to 22 years and possible associations with SARS-CoV-2 infection in Espírito Santo, Brazil. METHODS: This was a serial cross-sectional population-based study carried out from May to June 2020. The COVID-19 positivity rate was assessed by serological testing, and associated factors were assessed using Pearson's chi-square test (5% significance level). RESULTS: Among 1,693 individuals aged 2 to 22 years, 6.1% tested positive for COVID-19 and, among these, 35.5% did not present any symptoms. Differences were identified between positive and negative cases regarding the number of symptoms (p-value=0.001).Coughing was reported by 40.4% of positive individuals. Only 14.3% sought health care, namely 29.8% among those who tested positive and 13.3% among those who tested negative (p-value=0.001). CONCLUSION: The percentage of asymptomatic patients can impact the COVID-19 transmission chain in schools and fuel outbreaks of the disease in schools.

Prevalence of COVID-19 infection in the prison system in Espírito Santo/Brazil: persons deprived of liberty and justice workers. / Prevalência de infecção por COVID-19 no sistema prisional no Espírito Santo/Brasil: pessoas privadas de liberdade e trabalhadores da justiça.

OBJECTIVE: To present a prevalence study held in prisons and estimate the percentage of persons deprived of liberty, health professionals, and prison officers infected with SARS-CoV-2 in Espírito Santo (ES). METHODS: This is a prevalence study with a sample from 34 ES prisons, stratified between August 31 and September 4, 2020, following the Population-based age-stratified seroepidemiological investigation protocol for COVID-19 virus infection. The participants were interviewed and underwent rapid tests to detect immunoglobulin G and M in the groups mentioned. RESULTS: Among 1,830 individuals (311 health professionals, 675 prison officers, and 844 persons deprived of liberty - PDL), the prevalence of COVID-19 infection was 11.89% for health professionals, 22.07% for prison officers, and 31.64% for PDL. Most interviewees were male, aged 21 to 40 years, had completed elementary school and higher education, were multiracial, and situated in the Metropolitan area of Vitória. CONCLUSION: The prevalence was higher among persons deprived of liberty in the closed regime in all regions, as well as prison officers working in the semi-open regime, particularly in the North region. As for the comparison between regimes and regions, differences were identified between PDL groups with positive test results. Effectively combating COVID-19 within the prison system requires prison release actions, testing, and mass vaccination, as well as other health actions.

OBJETIVO: Apresentar um estudo de prevalência em presídios e estimar o percentual de pessoas privadas de liberdade, profissionais de saúde e agentes penitenciários infectados com o SARS-CoV-2 no Espírito Santo (ES). MÉTODOS: Tratou-se de um estudo de prevalência com amostragem realizada em 34 unidades prisionais no ES, estratificadas entre os dias 31 de agosto e 4 de setembro de 2020, com base no Population-based age-stratified seroepidemiological investigation protocol for COVID-19 virus infection. Realizaram-se entrevistas e testes rápidos para detecção de imunoglobina G e M nos grupos citados. RESULTADOS: Entre os 1.830 indivíduos (311 profissionais de saúde, 675 agentes penitenciários e 844 pessoas privadas de liberdade - PPL), as prevalências de infecção por COVID-19 foram 11,89% para os profissionais de saúde, 22,07% para os agentes penitenciários e 31,64% para as PPL. A maioria era do sexo masculino, com idade entre 21 a 40 anos, ensino fundamental e superior e cor parda, e os entrevistados concentravam-se na Região Metropolitana de Vitória. CONCLUSÃO: Observou-se que a prevalência foi maior entre as pessoas privadas de liberdade em todas as regiões no regime fechado e para os agentes penitenciários no regime semiaberto, com destaque para a Região Norte. Quanto à comparação entre os regimes e região, observaram-se distinções entre os grupos das PPL com testes positivos. Para que se alcance a eficácia no combate à COVID-19 no sistema prisional, são necessárias ações de desencarceramento, testes e vacinação em massa, como também outras ações de saúde.

School reopening and risks accelerating the COVID-19 pandemic: A systematic review and meta-analysis protocol.

BACKGROUND: One of the most recent concerns of this pandemic regards the role of schools reopening in disease transmission, as well as the impact of keeping schools closed. While school reopening seems critical for the education and mental health of children, adolescents, and adults, so far the literature has not systematically reached a consensus whether to recommend the return to schools in a way that would be safe for students and staff. OBJECTIVE: To synthesize and critically evaluate the scientific evidence on the potential risk of accelerating the Coronavirus Disease 2019 (COVID-19) pandemic among children, adolescents, young adults, and adults with school reopening. METHODS: This systematic review and meta-analysis protocol was elaborated following the PRISMA-P. We will include all observational study designs, which report on the potential risk of accelerating the COVID-2019 pandemic with school reopening. Electronic databases included were MEDLINE/PubMed, Cochrane Library, EMBASE, Web of Science, SCOPUS and CNKI. Additional sources will be also retrieved, including Clinical trials.gov-NIH, The British Library, Pro Quest Dissertations Database, Public Health Gray Literature Sources and Health Evidence, Google Scholar, and pre-prints [medRXiv]. No restriction to language or date will be used as search strategy. In an independently manner, two investigators will select studies, perform data extraction, as well as perform a critical appraisal of the risk of bias and overall quality of the selected observational studies, based on their designs. The heterogeneity among the studies will be assessed using the I2 statistic test. According to the results of this test, we will verify whether a meta-analysis is feasible. If feasibility is confirmed, a random-effect model analysis will be carried out. For data analysis, the calculation of the pooled effect estimates will consider a 95% CI and alpha will be set in 0.05 using the R statistical software, v.4.0.4. In addition, we will rate the certainty of evidence based on Cochrane methods and in accordance with the Grading of Recommendations Assessment, Development and Evaluation (GRADE). EXPECTED RESULTS: This systematic review and meta-analysis will provide better insights into safety in the return to school in the context of the COVID-2019 pandemic, at a time when vaccination advances unevenly in several countries around the world. Hence, consistent data and robust evidence will be provided to help decision-makers and stakeholders in the current pandemic scenario. PROSPERO REGISTRATION NUMBER: CRD42021265283; https://clinicaltrials.gov.

Living conditions, seroprevalence and symptoms of COVID-19 in slums in the Metropolitan Region of Vitória (Espírito Santo).

OBJECTIVES: to estimate the prevalence of SARS-CoV-2 infection in residents of the Greater Vitória region living in subnormal and non-subnormal agglomerates, and to compare sociodemographic and clinical characteristics of total residents (infected and not infected with SARS-CoV-2) between them. METHODS: Population-based prevalence study conducted by serological testing in 2020, with a study unit in households in Greater Vitória, grouped into census tracts classified as sub-normal agglomerates and non-sub-normal agglomerates. The two groups were compared in terms of prevalence and associated factors. The significance level adopted was 5%. RESULTS: The prevalence found in the sub-normal clusters was 12.05% (95%CI 9.59-14.50), and in the non-sub-normal clusters 10.23% (95%CI 7.97-12.50) this difference was not statistically significant (p = 0.273). Comparing the sociodemographic characteristics, more people who declare themselves to be of mixed race were found in the sub-normal clusters, a higher percentage of illiterates and people with only elementary education, greater number of residents per household, longer stay in public transportation, sharing a bathroom with another household, fewer bedrooms per residence and higher frequency of irregular water supply when compared to non-sub-normal clusters (p < 0.05). CONCLUSIONS: The epidemiological characteristics of sub-normal clusters' residents show the social inequalities that can hinder control measures in a pandemic situation.

Comorbidities and the risk of death among individuals infected by COVID-19 in Espírito Santo, Brazil.

INTRODUCTION: We investigated the association of self-reported comorbidities with fatality risk among individuals infected with Coronavirus disease 2019 (COVID-19) in Espírito Santo State, Brazil. METHODS: We included 212,620 individuals, ≥30 years old. The data were obtained from the COVID-19 panel. Kaplan-Meier curves and Cox regression model were used. RESULTS: COVID-19-positive individuals presenting with chronic conditions were at a higher risk of fatality than individuals without these comorbidities. Age had a significant effect on these relationships. CONCLUSIONS: Comorbidities were associated with an increased risk of fatality. Middle-aged people (30-59 years) with comorbidities should also be considered as a vulnerable group.

Spatial clustering and temporal trend analysis of international migrants diagnosed with tuberculosis in Brazil.

BACKGROUND: Tuberculosis (TB) in migrants is of concern to health authorities worldwide and is even more critical in Brazil, considering the country´s size and long land borders. The aim of the study was to identify critical areas in Brazil for migrants diagnosed with TB and to describe the temporal trend in this phenomenon in recent years. METHODS: This is an ecological study that used spatial analysis and time series analysis. As the study population, all cases of migrants diagnosed with TB from 2014 to 2019 were included, and Brazilian municipalities were considered as the unit of ecological analysis. The Getis-Ord Gi* technique was applied to identify critical areas, and based on the identified clusters, seasonal-trend decomposition based on loess (STL) and Prais-Winsten autoregression were used, respectively, to trace and classify temporal trend in the analyzed series. In addition, several municipal socioeconomic indicators were selected to verify the association between the identified clusters and social vulnerability. RESULTS: 2,471 TB cases were reported in migrants. Gi* analysis showed that areas with spatial association with TB in immigrants coincide with critical areas for TB in the general population (coast of the Southeast and North regions). Four TB clusters were identified in immigrants in the states of Amazonas, Roraima, São Paulo, and Rio de Janeiro, with an upward trend in most of these clusters. The temporal trend in TB in immigrants was classified as increasing in Brazil (+ 60.66% per year [95% CI: 27.21-91.85]) and in the clusters in the states of Amazonas, Roraima, and Rio de Janeiro (+1.01, +2.15, and + 2.90% per year, respectively). The cluster in the state of São Paulo was the only one classified as stationary. The descriptive data on the municipalities belonging to the clusters showed evidence of the association between TB incidence and conditions of social vulnerability. CONCLUSIONS: The study revealed the critical situation of TB among migrants in the country. Based on the findings, health authorities might focus on actions in regions identified, stablishing an intensive monitoring and following up, ensuring that these cases concluded their treatment and avoiding that they could spread the disease to the other regions or scenarios. The population of migrants are very dynamic, therefore strategies for following up them across Brazil are really urgent to manage the tuberculosis among international migrants in an efficient and proper way.

Mortalidad en personas ingresados en el hospital por COVID-19 en Espírito Santo, Brasil, 2020 Factors associated with COVID-19 hospital deaths in Espírito Santo, Brazil, 2020

Resumo Objetivo Analisar os fatores associados ao óbito em indivíduos internados por COVID-19 em hospitais do Espírito Santo, Brasil. Métodos Estudo transversal, com dados secundários. Modelos de regressão logística foram empregados para estimar razões de chance (odds ratio: OR) brutas e ajustadas. Resultados Até 14 de maio de 2020, 200 indivíduos receberam alta e 220 foram a óbito. Do total de pessoas estudadas, 57,1% eram do sexo masculino, 46,4% maiores de 60 anos de idade, 57,9% foram notificados por instituição privada e 61,7% apresentaram mais de 1 comorbidade. Na análise ajustada, a mortalidade hospitalar foi maior entre aqueles nas faixas etárias de 51 a 60 (OR=4,33 - IC95% 1,50;12,46) e mais de 60 anos (OR=11,84 - IC95% 4,31;32,54), notificados por instituição pública (OR=8,23 - IC95% 4,84;13,99) e com maior número de comorbidades (duas [OR=2,74 - IC95% 1,40;5,34] e três [OR=2,90 - IC95% 1,07;7,81]). Conclusão Observa-se maior mortalidade em idosos, com comorbidades e usuários de hospitais públicos. Resumen Objetivo Analizar los factores asociados con la mortalidad por COVID-19 en individuos ingresados en hospitales de Espírito Santo, Brasil. Métodos Estudio transversal. Los modelos de regresión logística estimaron una asociación de la mortalidad con características sociodemográficas, clínicas y de hospitalización. Resultados Hasta el 14 de mayo de 2020, 200 individuos fueron dados de alta y 220 murieron. Del número total de personas estudiadas, 57,1% eran hombres, 46,4% &gt;60 años, 57,9% notificados por una institución privada y 61,7% tenía más de 1 comorbilidad. Con respecto a la mortalidad, fue mayor en los grupos de edad de 51 a 60 años (odds ratio, OR=4,33 - IC95% 1,50;12,46) y los mayores de 60 años (OR=11,84 - IC95% 4,31;32,54), notificados por institución pública (OR=8,23 - IC95% 4,84;13,99) y con más número de comorbilidades (dos [OR=2,74 - IC95% 1,40;5,34] y tres [OR=2,90 - IC95%: 1,07;7,81]). Conclusión El análisis apunta a mayor mortalidad en adultos mayores, con comorbilidades y usuarios de hospitales públicos. Objective To analyze factors associated with the deaths of individuals hospitalized with COVID-19 in the state of Espírito Santo, Brazil. Methods This was a cross-sectional study using secondary data. Logistic regression models were used to estimate crude and adjusted odds ratios (OR). Results As at May 14, 2020, 200 individuals had been discharged and 220 had died. Of the total number of people studied, 57.1% were male, 46.4% were &gt;60 years old, 57.9% were cases notified by a private institution, and 61.7% had &gt;1 comorbidity. In the adjusted analysis, hospital mortality was higher for the 51-60 age group (OR=4.33 - 95%CI 1.50;12.46), the over 60 age group (OR=11.84 - 95%CI 4.31;32.54), cases notified by public institutions (OR=8.23 - 95%CI 4.84;13.99) and cases with a greater number of comorbidities (two [OR=2.74 - 95%CI 1.40;5.34] and three [OR=2.90 - 95%CI 1.07;7.81]). Conclusion Higher mortality was found in older individuals, those with comorbidities and users of public hospitals.

Factors associated with COVID-19 hospital deaths in Espírito Santo, Brazil, 2020. / Fatores associados ao óbito hospitalar por COVID-19 no Espírito Santo, 2020.

OBJECTIVE: To analyze factors associated with the deaths of individuals hospitalized with COVID-19 in the state of Espírito Santo, Brazil. METHODS: This was a cross-sectional study using secondary data. Logistic regression models were used to estimate crude and adjusted odds ratios (OR). RESULTS: As at May 14, 2020, 200 individuals had been discharged and 220 had died. Of the total number of people studied, 57.1% were male, 46.4% were >60 years old, 57.9% were cases notified by a private institution, and 61.7% had >1 comorbidity. In the adjusted analysis, hospital mortality was higher for the 51-60 age group (OR=4.33 - 95%CI 1.50;12.46), the over 60 age group (OR=11.84 - 95%CI 4.31;32.54), cases notified by public institutions (OR=8.23 - 95%CI 4.84;13.99) and cases with a greater number of comorbidities (two [OR=2.74 - 95%CI 1.40;5.34] and three [OR=2.90 - 95%CI 1.07;7.81]). CONCLUSION: Higher mortality was found in older individuals, those with comorbidities and users of public hospitals.